Citrein 50 Hot Sterilant (Citric Acid 50%): Powerful Thermal Disinfection for Hemodialysis Excellence
Citrein 50 Hot Sterilant, featuring 50% citric acid concentration, delivers comprehensive thermal disinfection, cleaning, and decalcification for hemodialysis machines. Proven effective against bacteria, viruses, fungi, and mycobacteria at 83°C, this high-strength acid cleaner ensures optimal machine performance and patient safety. Trust in the proven power of citric thermal disinfection technology.
Citrein 50 is a liquid concentrate for the citric thermal disinfection, cleaning, and decalcification of hemodialysis machines, providing comprehensive machine maintenance in a single solution. The high-strength 50% citric acid concentration delivers powerful thermal disinfection and scale removal for hemodialysis equipment while being safe, efficient, and biodegradable. The solution effectively combines three critical functions: sterilization, cleaning, and decalcification, ensuring optimal machine performance and extending equipment lifespan.
2. Indications
Citrein 50 (Citric Acid 50%) Hot Sterilant is indicated for:
Thermal disinfection of hemodialysis machine fluid pathways
Cleaning and decalcification of dialysis equipment
Heat sterilization protocols in renal care facilities
Regular maintenance of Fresenius and other dialysis machines with hot sterilization provision
Prevention of mineral buildup and biofilm formation
Comprehensive disinfection cycles as part of infection control protocols
3. How it Works
Thermal Disinfection Mechanism: Citric acid works through thermal disinfection at elevated temperatures (83°C), where the combination of heat and acid creates a hostile environment for microorganisms. The solution achieves comprehensive microbial kill through protein denaturation and cellular disruption at high temperatures.
Decalcification Action: The citric acid chelates calcium and magnesium ions, effectively dissolving mineral deposits and scale buildup in machine fluid pathways, maintaining optimal flow rates and preventing equipment damage.
Multi-Modal Action: Working concentration of 3% Citric Acid 50% at 83°C with 15-minute exposure time provides bactericidal, fungicidal, tuberculocidal, and virucidal properties including effectiveness against HBV, HCV, and HIV.
4. Quality and Safety
Manufacturing Standards: Available from multiple manufacturers including B. Braun, Nipro, and other medical device companies, produced under strict pharmaceutical standards ensuring consistent quality and performance.
Regulatory Compliance: Meets European standards EN 13727/14561, EN 13624/14562, EN 14348/14563, and EN 14476, demonstrating comprehensive antimicrobial efficacy at specified conditions.
Environmental Safety: Biodegradable formulation that breaks down safely after use, reducing environmental impact while maintaining superior disinfection performance.
Quality Assurance: Each batch undergoes rigorous testing to ensure consistent concentration and antimicrobial effectiveness, with documented test reports verifying performance standards.
5. Important Considerations
Operating Parameters:
Temperature: 83°C for optimal disinfection
Exposure Time: 15 minutes minimum contact time
Working Concentration: 3% dilution of Citric Acid 50%
Packaging: Available in 6L and 10L canisters for facility convenience
Antimicrobial Spectrum:
Bactericidal: Effective against vegetative bacteria
Fungicidal: Active against fungal pathogens
Tuberculocidal/Mycobacteriacidal: Kills mycobacteria including TB
Virucidal: Inactivates enveloped and non-enveloped viruses including hepatitis viruses and HIV
Usage Protocol:
Dilute concentrate to working concentration per manufacturer instructions
Ensure adequate temperature (83°C) and contact time (15 minutes)
Follow machine-specific protocols for thermal disinfection cycles
Complete with appropriate rinsing procedures post-disinfection
Storage Requirements:
Store concentrate in cool, dry environment
Protect from extreme temperatures and direct sunlight
Keep containers tightly closed when not in use
Check expiration dates and rotate stock appropriately
Safety Precautions:
Handle concentrate with appropriate personal protective equipment
Ensure adequate ventilation during preparation and use
Follow facility protocols for chemical handling and disposal
Monitor temperature and timing parameters for effectiveness
Professional Considerations:
Requires trained personnel familiar with thermal disinfection procedures
Integration with overall machine maintenance and infection control programs
Regular monitoring of solution concentration and temperature parameters
Documentation of disinfection cycles for quality assurance
Professional Note: Citrein 50 Hot Sterilant represents a comprehensive solution for hemodialysis machine maintenance, combining powerful disinfection with essential cleaning and decalcification functions. Healthcare facilities should ensure proper training, monitoring, and documentation protocols to maximize effectiveness and maintain patient safety standards.
