MDT Plus 4 Cold Sterilant

MDT Plus 4 Cold Sterilant

1. Key Benefits

MDT Plus 4 is a stabilized peracetic acid product that offers state-of-the-art cold sterilization and is widely used for reprocessing of dialyzers. The formulation provides rapid action against all microorganisms while enhancing removal of organic material and leaving no harmful residue. As a strong oxidant, the solution readily cleans all cellular debris, precipitates, and scale in machines when used routinely, combining high-level disinfection with equipment maintenance in a single application.

2. Indications

MDT Plus 4 Cold Sterilant is indicated for:

• High-level disinfection and sterilization of dialyzers during reprocessing
• Cold sterilization of hemodialysis equipment and accessories
• Disinfection of dialysis machine fluid pathways between patient treatments
• Decontamination of heat-sensitive medical equipment
• Prevention of biofilm formation in dialysis systems
• Comprehensive microbial control including bacteria, viruses, fungi, and mycobacteria

3. How it Works

Active Components: Contains Peracetic Acid 4% w/w, Hydrogen Peroxide 21% w/w, and Acetic Acid 10% w/w in a stabilized formulation (CH3COOOH). Peracetic acid is characterized by rapid action against all microorganisms through powerful oxidation that disrupts cellular structures and enzymatic processes.

Cold Sterilization Process: Effective as a cold sterilant with extended contact time protocols, eliminating the need for heat activation while achieving comprehensive microbial kill. The solution penetrates biofilms and organic matter, ensuring thorough decontamination of complex equipment surfaces.

Environmental Safety: Special advantages include lack of harmful decomposition products, breaking down into acetic acid, water, oxygen, and hydrogen peroxide – all environmentally safe compounds.

4. Quality and Safety

Manufacturing Excellence: Manufactured by Meditop Co. Ltd., Thailand, under pharmaceutical-grade quality control standards ensuring consistent potency and stability.

Antimicrobial Spectrum: Effective against non-tuberculous mycobacteria including HIV (associated with AIDS), hepatitis viruses, and other pathogenic microorganisms when used as directed. Provides broad-spectrum antimicrobial activity across bacteria, viruses, fungi, and spores.

Safety Profile: Leaves no harmful residues after proper use and rinsing protocols. The oxidizing action breaks down organic contaminants while the decomposition products are environmentally benign.

5. Important Considerations

Technical Specifications:

• Peracetic Acid: 4% w/w active concentration
• Hydrogen Peroxide: 21% w/w oxidizing agent
• Acetic Acid: 10% w/w stabilizing component
• Product Code: MDT-PAA-4
• Classification: Concentrated Cold Sterilant/High Level Disinfectant

Usage Protocol:

• Follow manufacturer’s dilution and contact time recommendations
• Ensure adequate contact time for sterilization (typically several hours)
• Complete with thorough rinsing procedures using appropriate test strips
• Document sterilization cycles for quality assurance compliance

Monitoring Requirements:

• Use Serim Guardian Residual Peroxide Test Strips to verify complete removal after rinsing
• Regular testing of disinfectant potency and residual levels
• Documentation of sterilization parameters and test results
• Quality control monitoring per facility protocols

Storage and Handling:

• Store concentrate in cool, dry environment away from incompatible materials
• Protect from direct sunlight and temperature extremes
• Handle with appropriate personal protective equipment
• Ensure adequate ventilation during preparation and use

Safety Precautions:

• Strong oxidant requiring careful handling per manufacturer recommendations
• Avoid contact with incompatible materials and reducing agents
• Implement proper ventilation and personal protection protocols
• Emergency procedures should be established for accidental exposure

Professional Considerations:

• Requires trained personnel familiar with cold sterilization procedures
• Integration with comprehensive infection control programs essential
• Regular equipment maintenance and calibration recommended
• Compliance with local regulations for chemical disinfectant use

Professional Note: MDT Plus 4 Cold Sterilant represents advanced peracetic acid technology for dialysis facility safety. Healthcare providers should ensure proper training on handling, dilution, contact time requirements, and residual testing protocols to maximize effectiveness while maintaining patient and staff safety.

References

1. MDT Plus 4 Cold Sterilant Product Information – Meditop Co. Ltd., Thailand
2. “Chemical Disinfectants” – Centers for Disease Control and Prevention, August 2024
3. Philippines Government Tender Specifications for MDT Plus 4 Cold Sterilant – May 2022
4. Sceptre Medical India Private Limited Product Documentation
5. “Peracetic Acid – an overview” – ScienceDirect Topics
6. “Disinfectants in a Hemodialysis Setting” – Frontiers in Cellular and Infection Microbiology, March 2021
7. FDA Philippines Medical Device Registration Database